Prof. František Štěpánek, Ph.D.

Department of Chemical Engineering
University of Chemistry and Technology, Prague

http://www.vscht.cz/chobotix
 

Prof. Frantisek Stepanek obtained his PhD in chemical engineering in 2000 jointly from the University of Chemistry and Technology in Prague and Université Pierre et Marie Curie in Paris. He worked at Unilever R&D in the, later moving to Imperial College London where he established a research group on particle technology. Since 2008 he is a professor of chemical engineering at the UCT Prague. Since 2019 he is the scientific director of The Pharmaceutical Applied Research Centre (PARC). His research interests include drug delivery, pharmaceutical process engineering and chemical robotics. Prof. Stepanek has received several awards for his work including the Moulton Medal, the Friedrich Wilhelm Bessel Award, the Philip Leverhulme Prize, the Werner von Siemens Award or the Fulbright Fellowship.

Selected publications:
 
  • Lizoňová D., Frei S., Balouch M., Zadražil A., Štěpánek F., “Multilobed magnetic liposomes enable remotely controlled collection, transport and delivery of membrane soluble cargo to vesicles and cells” ACS Appl. Bio Mater. 4, 4833-4840 (2021)
  • Ruphuy G., Saloň I., Tomas J., Šalamúnová P., Hanuš J., Štěpánek F., “Encapsulation of poorly soluble drugs in yeast glucan particles by spray drying improves dispersion and dissolution properties”, Int. J. Pharm. 576, 118990 (2020)
  • Saloň I., Bajgar A., Krejčová G., Doležal T., Jindra M., Štěpánek F., “Yeast glucan particles enable intracellular protein delivery in Drosophilawithout compromising the immune system”, Biomater. Sci. 7, 4708-4719 (2019)
  • Haša J., Hanuš J., Štěpánek F., “Magnetically controlled liposome aggregates for on-demand release of reactive payloads”, ACS Appl. Mater. Interfaces 10, 20306–20314 (2018)
  • Lizoňová D., Mužík J., Šoltys M., Beránek J., Kazarian S.G., Štěpánek F., “Molecular-level insight into hot-melt loading and drug release from mesoporous silica carriers”, Eur. J. Pharm. Biopharm. 130, 327-335 (2018)

Full list of over 200 publications:
https://www.chobotix.cz/publications/journal-articles/